import matplotlib.pyplot as plt
from skimage import io

photo = io.imread('../images/waldo.jpg')
type(photo)

plt.imshow(photo)
<matplotlib.image.AxesImage at 0x7f390b168460>
import matplotlib.pyplot as plt
from skimage import io

photo = io.imread('../images/waldo.jpg')
type(photo)

plt.imshow(photo)
plt.imshow(photo[210:350, 425:500])
<matplotlib.image.AxesImage at 0x7f393c320ca0>

As seen above, I have successfully sliced the image to find Waldo. He's quite the guy.